BiophysicsACS Central SciencePeer-reviewed
Post-Translational Modifications Control Phase Transitions of Tau
Wyatt C. Powell, McKinley Nahum, Karl Pankratz…·Maciej A. A. Walczak
This study investigates how AD-specific post-translational modifications affect Tau self-assembly into PHFs, finding that phosphorylation generally inhibits aggregation while acetylation has variable effects.