Synthetic BiologybioRxivPreprint
Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform
Christophe Gaillochet, Alexandra Peña Fernández, Vera Goossens…·Thomas B. Jacobs
The paper develops an optimized LbCas12a-ABE base editor in wheat and maize using the ITER platform, achieving 40% activity on a GFP reporter through iterative design.
4 citations