A Broad-Spectrum Chemokine Inhibitor Prevents Preterm Labor in Mice by Suppressing Inflammation Induced by Intra-Amniotic Injection of Interleukin-1 alpha
Adam Boros-Rausch, Nicole Ballan, Isabella Celik, Anna Dorogin, Zoe E. Gillespie, Jennifer A. Mitchell, David J. Grainger, David Fox, Oksana P. Shynlova, Stephen James Lye
This study shows that BSCI prevents preterm labor in mice by reducing inflammation and uterine gene expression changes caused by IL-1.
bioRxiv · Oct 17, 2026 · PreprintPhysiology