Molecular BiologyMolecular CellPeer-reviewed
Single-molecule imaging of telomerase RNA reveals a Recruitment-Retention model for telomere elongation
Hadrien Laprade, Emmanuelle Querido, Michael J. Smith…·Agnel J. Sfeir
This study uses single-molecule imaging to reveal a Recruitment-Retention model for telomere elongation, showing how hTERT and TPP1 regulate hTR dynamics and how mutations affect telomere homeostasis.