Author

David Ledoux

Staten Island University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Chunyan LiiD· 2 shared Kaitlyn Rams· 2 shared Keren Powell· 2 shared Ping WangiD· 2 shared Steven Wadolowski· 2 shared Amir Dehdashti· 1 shared Amir R Dehdashti· 1 shared Bernadette Tam· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Chunyan LiORCID

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2 papers

Recent·Most cited

An Innate Neuroprotective Reflex Activates NRF2 via Phosphorylation of p62 at Ser351 to Mitigate Traumatic Brain Injury

Chunyan Li, Keren Powell, Steven Wadolowski, David LeDoux, Amir R Dehdashti, Jamie S Ullman, Max Brenner, Christopher LeDoux, Kaitlyn Rams, Daniel Sciubba, Ping Wang

This paper shows that artificial diving reflex via trigeminal nerve stimulation activates NRF2 through p62 phosphorylation, offering neuroprotection in traumatic brain injury without depleting antioxidant reserves.

bioRxiv · Nov 4, 2026 · PreprintNeuroscience

Trigeminal Nerve Stimulation Attenuates Traumatic Brain Injury-Induced Neuronal Damage via CGRP-PINK1 Mitophagy Axis

Chunyan Li, Keren Powell, Steven Wadolowski, Junhwan Kim, Kaitlyn Rams, Bernadette Tam, Amir Dehdashti, Jamie S. Ullman, David Ledoux, Lance B. Becker, Ping Wang

This paper shows that trigeminal nerve stimulation reduces traumatic brain injury-induced neuronal damage by preserving mitochondrial function through the CGRP-PINK1 mitophagy pathway.

bioRxiv · Oct 13, 2026 · PreprintNeuroscience