Author

David Lyons

University of Aberdeen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alasdair T. S. Leeson-PayneiD· 1 shared Brian LamiD· 1 shared Claudia CristianoiD· 1 shared Daniel I. BrierleyiD· 1 shared Fiona M. GribbleiD· 1 shared Frank M. ReimanniD· 1 shared Georgina K.C. DowsettiD· 1 shared Giles S.H. YeoiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alasdair T. S. Leeson-PayneORCID

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1 paper

Recent·Most cited

Obesity medication lorcaserin requires brainstem GLP-1 neurons to reduce food intake in mice

Stefan Wagner, Daniel I. Brierley, Alasdair T. S. Leeson-Payne, Wanqing Jiang, Raffaella Chianese, Brian Lam, Georgina K.C. Dowsett, Claudia Cristiano, David Lyons, Frank M. Reimann, Fiona M. Gribble, Giles S.H. Yeo, Stefan Trapp, Lora K. Heisler

This study identifies brainstem GLP-1 neurons as essential for lorcaserin's effect on reducing food intake in mice and suggests combination therapy with GLP-1R agonists may enhance efficacy.

bioRxiv · May 6, 2022 · PreprintNeuroscience