Author

Wanqing Jiang

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel I. BrierleyiD· 2 shared Fiona Mary GribbleiD· 2 shared Frank M. ReimanniD· 2 shared Stefan TrappiD· 2 shared Alasdair T. S. Leeson-PayneiD· 1 shared Brian LamiD· 1 shared Cecilia SkougiD· 1 shared Claudia CristianoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Daniel I. BrierleyORCID

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2 papers

Recent·Most cited

Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice

Wanqing Jiang, Cecilia Skoug, Ian Rodrigues, Ernesto Ciabatti, Fiona Mary Gribble, Frank M. Reimann, Daniel I. Brierley, Marie K. Holt, Stefan Trapp

This study shows that chronic activation of GLP-1 neurons in the brainstem reduces food intake and causes sustained weight loss in obese mice.

Molecular Metabolism · Mar 4, 2026Peer-reviewedNeuroscience

Obesity medication lorcaserin requires brainstem GLP-1 neurons to reduce food intake in mice

Stefan Wagner, Daniel I. Brierley, Alasdair T. S. Leeson-Payne, Wanqing Jiang, Raffaella Chianese, Brian Lam, Georgina K.C. Dowsett, Claudia Cristiano, David Lyons, Frank M. Reimann, Fiona M. Gribble, Giles S.H. Yeo, Stefan Trapp, Lora K. Heisler

This study identifies brainstem GLP-1 neurons as essential for lorcaserin's effect on reducing food intake in mice and suggests combination therapy with GLP-1R agonists may enhance efficacy.

bioRxiv · May 6, 2022 · PreprintNeuroscience