Molecular and Structural Basis of Cardiac Remodelling in Niemann-Pick Type C
Qianqian Song, Ishika Prachee, Karolina M. Stępień, Neil Herring, Alfonso Bueno‐Orovio, Rebecca A. Capel, David Priestman, Thamali Ayagama, Laura Bell, Victoria S Rashbrook, Reuben Bush, Duncan Burnaby Sparrow, C S Smith, Dave Smith, Emily Akerman, , Rebecca A.B. Burton
This study identifies cardiac involvement in Niemann-Pick type C through ECG abnormalities, fibrosis, and transcriptomic changes in patients and Npc1-/- mice.
bioRxiv · Jul 9, 2026 · PreprintPhysiology