Author

David Shire

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Martin A. PicardiD· 3 shared Caroline TrumpffiD· 2 shared Qiuhan HuangiD· 2 shared Alan Arthur CoheniD· 1 shared Alex JunkeriD· 1 shared Anna Sophia MonzeliD· 1 shared Ayelet M RosenbergiD· 1 shared Catherine E. MonkiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersPhysiology

Martin A. PicardORCID

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Author profile →

3 papers

Recent·Most cited

Brain-body mitochondrial distribution patterns lack coherence and point to tissue-specific and individualized regulatory mechanisms

Jack Devine, Anna Sophia Monzel, David Shire, Ayelet M Rosenberg, Alex Junker, Alan Arthur Cohen, Martin A. Picard

The paper examines mitochondrial distribution patterns across tissues and finds they lack coherence, suggesting tissue-specific and individualized regulatory mechanisms.

Life Metabolism · Apr 2, 2025Peer-reviewedCell Biology

Blood mitochondrial health markers cf-mtDNA and GDF15 in human aging

Caroline Trumpff, Qiuhan Huang, Jeremy Michelson, Cynthia C. Liu, David Shire, Christian Georg Habeck, Yaakov Stern, Martin A. Picard

The paper examines cf-mtDNA and GDF15 as potential biomarkers of mitochondrial health in aging, finding GDF15 correlates with age and diabetes while cf-mtDNA does not.

bioRxiv · Jan 28, 2025 · PreprintPhysiology

Associations between prenatal distress, mitochondrial health, and gestational age: findings from two pregnancy studies in the USA and Turkey

Qiuhan Huang, David Shire, Fiona Hollis, Sameera Abuaish, Martin A. Picard, Catherine E. Monk, Elif Aysimi Duman, Caroline Trumpff

This study examines associations between mitochondrial markers, maternal distress, and pregnancy outcomes in two cohorts, finding correlations between GDF15 levels and gestational age and BMI.

Mitochondrion · Oct 16, 2024Peer-reviewedPhysiology