Jeremy Michelson

Electron microscopy visualization of cell-free mitochondrial DNA-containing extracellular vesicles in human plasma, serum, and saliva

The paper uses electron microscopy to analyze mitochondrial DNA-containing extracellular vesicles in human biofluids, showing that cf-mtDNA is often associated with double-membrane particles.

Blood mitochondrial health markers cf-mtDNA and GDF15 in human aging

The paper examines cf-mtDNA and GDF15 as potential biomarkers of mitochondrial health in aging, finding GDF15 correlates with age and diabetes while cf-mtDNA does not.

The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress

This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.

MitoQuicLy: a high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva

MitoQuicLy quantifies cf-mtDNA in plasma, serum, and saliva with high agreement to column-based methods, showing significant inter-individual and biofluid-specific differences.