BioengineeringbioRxivPreprint
Dual Ethanolamine Head Groups in Ionizable Lipids Facilitate Phospholipid-free Stable Nanoparticle Formulation for Augmented and Safer mRNA Delivery
Jing Lu, Ting Jiang, Xuechun Li…·Jinzhong Lin
This paper introduces ionizable lipids with dual ethanolamine head groups for phospholipid-free mRNA delivery, showing improved stability, efficiency, and reduced toxicity.
DOI 10.1101/2023.10.13.562139