High-Complexity Barcoded Rabies Virus for Scalable Circuit Mapping Using Single-Cell and Single-Nucleus Sequencing
David Shin, Madeleine E. Urbanek, H. Hanh Larson, Anthony J. Moussa, Kevin Y. Lee, Donovan L Baker, Elio Standen-Bloom, Sangeetha Ramachandran, Derek Bogdanoff, Cathryn René Cadwell, Tomasz Jan Nowakowski
The paper introduces a method to map neuronal circuits using barcoded rabies virus and single-nucleus RNA sequencing, revealing cell-type-specific circuit motifs in developing human cerebral cortex.
bioRxiv · Oct 1, 2024 · PreprintNeuroscience