Bryant B. Chhun

This paper introduces Oblique Line Scan (OLS) illumination to enhance single-molecule tracking in living cells and solution, enabling high-throughput and sensitive protein dynamics measurements.

DynaMorph uses self-supervised learning to analyze morphodynamic states of live human microglia, identifying distinct states and transitions in response to disease-relevant stimuli.

This study maps human microglia development and identifies cytokine-associated subtypes and functional roles in neural network maturation.