Author

Derek Elli

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:multiome· 1

Frequent Co-Authors

Dominique M. MissiakasiD· 2 shared Aaron Esser-Khan· 1 shared Alison M. DevaultiD· 1 shared Ani SolankiiD· 1 shared Ann G. CarmichaeliD· 1 shared Anne Dumaine· 1 shared Christian E. DemeureiD· 1 shared Chun YeiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Dominique M. MissiakasORCID

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2 papers

Recent·Most cited

Polymer-lipid hybrid nanoparticle enhances mRNA delivery and T cell-mediated immunity

Xiaolei Cai, Min Chen, Guoshuai Cao, Nicholas W. Asby, Derek Elli, Haley Gula, Vlad I. Nicolaescu, Duy-Thuc Nguyen, Xiaodan Huang, Tanushree Dangi, Ani Solanki, Sara Woessner, Wenbo Zhang, Erting Tang, Lisa R. Volpatti, , Jun Huang

This study develops a polymer-lipid hybrid nanoparticle (PLNP) to enhance mRNA delivery and T cell immunity, showing improved antigen-specific T cell responses and protection against viral variants and cancer.

bioRxiv · Jan 24, 2026 · PreprintImmunology

Reply to Barton et al: signatures of natural selection during the Black Death

Tauras P. Vilgalys, Jennifer Klunk, Christian E. Demeure, Xiaoheng Cheng, Mari Shiratori, Julien Madej, Rémi Beau, Derek Elli, Maria I. Patino, Rebecca C. Redfern, Sharon N. DeWitte, Julia A. Gamble, Jesper L. Boldsen, Ann G. Carmichael, Nükhet Varlık, , Luis Bruno Barreiro

The paper addresses statistical concerns about detecting natural selection during the Black Death using ancient genomic data, reaffirming findings related to immune loci and the ERAP2 variant.

bioRxiv · Apr 6, 2023 · PreprintGenomics