Author

Julien Madej

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Javier Pizarro‐CerdáiD· 4 shared Rémi Beau· 4 shared Cyril SaviniD· 3 shared Pierre Lê-BuryiD· 3 shared Anne DerbiseiD· 2 shared Christian E. DemeureiD· 2 shared Guillem Mas FioliD· 2 shared Marion LemarignieriD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMicrobiology

Javier Pizarro‐CerdáORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Yersinia pestis lipoprotein SlyB promotes plague pathogenesis via envelope stress tolerance

Pierre Lê-Bury, Emelyne Bougit, Sébastien Bontemps‐Gallo, Guillem Mas Fiol, Cyril Savin, Van Son Nguyen, Julien Madej, Rémi Beau, Caroline Buscail, Nicolas Jean Bouladoux, Friederike Jönsson, COSIPOP study group, Marion Lemarignier, Mara Emilia Carloni, Anne Derbise, , Olivier Dussurget

This study identifies SlyB as a key lipoprotein in Yersinia pestis that enhances envelope stress tolerance, enabling immune evasion in mammalian hosts but not in flea vectors.

bioRxiv · Jun 9, 2026 · PreprintMicrobiology

A type IVB secretion system contributes to the pathogenicity of Yersinia pseudotuberculosis strains responsible for the Far East scarlet-like fever

Marion Lemarignier, Cyril Savin, Inés Ruedas‐Torres, Anne Derbise, Charles Coluzzi, Jose Pablo Marin‐Obando, Josue Barquero-Chavarria, Pierre Lê-Bury, Julien Burlaud‐Gaillard, Julien Madej, Rémi Beau, Philippe Roingeard, Paul Lechat, Eduardo P. C. Rocha, Jaime Gómez-Laguna, Javier Pizarro‐Cerdá

This study identifies the Y. pseudotuberculosis T4BSS as a virulence factor contributing to FESLF pathogenicity through immune modulation during oral infection.

microLife · Jan 1, 2026Peer-reviewedMicrobiology

In-host evolution of Yersinia enterocolitica during a chronic human infection

Cyril Savin, Pierre Lê-Bury, Julien Guglielmini, Thibaut Douché, Guillem Mas Fiol, Rodolphe Buzelé, Cécile Le Brun, Frédéric Bastides, Maud François, Béatrice Birmelé, Laura Guichard, Julien Madej, Rémi Beau, Nicolas Cabanel, Laurent Dortet, , Javier Pizarro‐Cerdá

This study tracks genetic and phenotypic changes in Yersinia enterocolitica during a chronic human infection, revealing host-adaptive mutations and antibiotic resistance mechanisms.

Nature Communications · Jul 1, 2025Peer-reviewedMicrobiology

Reply to Barton et al: signatures of natural selection during the Black Death

Tauras P. Vilgalys, Jennifer Klunk, Christian E. Demeure, Xiaoheng Cheng, Mari Shiratori, Julien Madej, Rémi Beau, Derek Elli, Maria I. Patino, Rebecca C. Redfern, Sharon N. DeWitte, Julia A. Gamble, Jesper L. Boldsen, Ann G. Carmichael, Nükhet Varlık, , Luis Bruno Barreiro

The paper addresses statistical concerns about detecting natural selection during the Black Death using ancient genomic data, reaffirming findings related to immune loci and the ERAP2 variant.

bioRxiv · Apr 6, 2023 · PreprintGenomics