Author

Devorah Cahn

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Assay:flow cytometry· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Gregg A. DuncaniD· 3 shared Matthew T. WolfiD· 3 shared Alexa SterniD· 2 shared Christopher M. JewelliD· 1 shared Michael J. BuckenmeyeriD· 1 shared Nimit L. PateliD· 1 shared Sahana KumariD· 1 shared Sanjay PaliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioengineering

Gregg A. DuncanORCID

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Author profile →

3 papers

Recent·Most cited

Barrier Function of the Extracellular Matrix in AAV Gene Therapy

Yahya Cheema, Devorah Cahn, Sahana Kumar, Matthew T. Wolf, Gregg A. Duncan

This study investigates how the extracellular matrix affects AAV gene therapy by comparing diffusion and transduction efficiency across different AAV serotypes and ECM models.

Cellular and Molecular Bioengineering · Jan 24, 2026Peer-reviewedBioengineering

PEGylation strategies for enhanced nanoparticle delivery to tumor associated immune cells

Devorah Cahn, Sanjay Pal, Alexa Stern, Nimit L. Patel, Timothy Gower, Senta M. Kapnick, Christopher M. Jewell, Gregg A. Duncan, Matthew T. Wolf

This study evaluates how linear and branched PEGylation affects nanoparticle uptake and distribution in tumor and immune cells, showing branched PEG increases spleen accumulation and linear PEG enhances tumor uptake by immune cells.

Bioengineering & Translational Medicine · Dec 10, 2025Peer-reviewedBioengineering

The Extracellular Matrix Limits Nanoparticle Diffusion and Cellular Uptake in a Tissue-Specific Manner

Devorah Cahn, Alexa Stern, Michael J. Buckenmeyer, Matthew T. Wolf, Gregg A. Duncan

This study investigates how tissue-specific ECM properties affect nanoparticle diffusion and cellular uptake, finding that PEGylation strategy impacts ECM penetration and uptake differently across tissues.

ACS Nano · Nov 5, 2024Peer-reviewedBioengineering