GenomicsbioRxivPreprint
A local sequence signature defines a subset of heterochromatin-associated CpGs with minimal loss of methylation in healthy tissues but extensive loss in cancer
Dror Bar, Lior Fishman, Yueyuan Zheng…·Benjamin P. Berman
The paper identifies a sequence signature that predicts CpG methylation loss in healthy tissues and cancer, revealing slow-loss CpGs with minimal methylation loss in health but significant loss in cancer.
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