Author

Diana C. Beard

Novartis (Switzerland)Primary ORCID profile (0000-0002-1799-0771 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Diana C. BeardiD2 papers · Washington University in St. Louis

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Brynne Currier· 1 shared Christian E. StiegeriD· 1 shared Daniel K. NomuraiD· 1 shared Dustin DovalaiD· 1 shared Erin L. LiiD· 1 shared Francisco J. Garcia· 1 shared Hannah T. Rosen· 1 shared Jeffrey M. McKennaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Brynne Currier

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1 paper

Recent·Most cited

Cancer BiologyAngewandte Chemie International EditionPeer-reviewedSep 25, 2025

Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

Hannah T. Rosen, Kelvin Li, Christian E. Stieger…·Daniel K. Nomura

This paper identifies a sulfinyl aziridine compound that selectively degrades MYC by targeting specific residues in its intrinsically disordered regions, demonstrating the potential of chiral small molecules for targeting undruggable proteins.

15 citationstop 4%

humanexperimental assay

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