GenomicsbioRxivPreprint
Single Molecule Sequencing of Cell-free DNA from Maternal Plasma for Noninvasive Trisomy Detection
Minyue Dong, Liwei Deng, Huan Jin…·Jiankui He
This study uses single molecule sequencing of cell-free DNA from maternal plasma to detect trisomy 13, 18, and 21 with improved sensitivity and reduced GC bias compared to NGS.
2 citations