Author

Dimitri Joseph

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam A LauveriD· 1 shared Adam J Moesers· 1 shared Alfred Jay RobisoniD· 1 shared Benjamin Scott GlicksbergiD· 1 shared Bin CheniD· 1 shared Brianna Smith· 1 shared Dmitry R. LeshchineriD· 1 shared Eric J. NestleriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

Adam A LauverORCID

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2 papers

Recent·Most cited

In Vivo Transcriptomics-Based Framework for Systematic Indication Expansion

Zsolt Palmer, Shubham Koirala, Nabasmita Talukdar, Xiaodan Zhang, Hannah S. Garver, McKenzie Mahlmeister, Li Huang, Dimitri Joseph, Dmitry R. Leshchiner, Rama Shankar, Stephanie Wengert Watts, Xiaopeng Li, Benjamin Scott Glicksberg, Adam A Lauver, Bin Chen

This paper presents a drug repurposing framework using in vivo transcriptomics to expand indications by matching drug signatures with disease signatures, successfully recovering established uses of semaglutide and proposing new ones.

bioRxiv · Oct 14, 2026 · PreprintSystems Biology

FosB/ΔFosB activation in mast cells regulates gene expression to modulate allergic inflammation in male mice

Natalia Duque‐Wilckens, Dimitri Joseph, Meesum Syed, Brianna Smith, Nidia C Maradiaga, Szu-Ying Yeh, Vidhula Srinivasan, Fabiola Sotomayor, Kait Durga, Eric J. Nestler, Adam J Moesers, Alfred Jay Robison

This study shows that FosB/ΔFosB in mast cells regulates gene expression to reduce allergic inflammation in male mice by enhancing DUSP4 expression.

bioRxiv · May 6, 2024 · PreprintImmunology