GenomicsPLOS GeneticsPeer-reviewed
Accelerating gene discovery by phenotyping whole-genome sequenced multi- mutation strains and using the sequence kernel association test (SKAT)
Tiffany A Timbers, Stephanie J Garland, Swetha Mohan…·Michel R Leroux
The paper uses a whole-genome sequenced multi-mutation C. elegans library with SKAT to identify genes associated with ciliated sensory neuron defects, uncovering novel genes like BGNT-1.1 linked to human ciliopathies.
DOI 10.1371/journal.pgen.1006235