Cancer BiologybioRxivPreprint
Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy
Lei Wang, Yufeng Xiao, Yuewan Luo…·Weizhou Zhang
This paper develops a PROTAC molecule (NR-V04) that degrades NR4A1, leading to tumor inhibition and immune modulation in melanoma.
DOI 10.1101/2023.08.09.552650