BioinformaticsbioRxivPreprint
Spatial multi-omic profiling of non-autonomous transcriptomic and epigenomic responses to genetic perturbation
Javid Ghaemmaghami, Kun H Lee, Shean Jiang…·Joshua D Welch
This study introduces Perturb-Tags, a spatial multi-omic technique for CRISPR screening, revealing non-autonomous gene expression changes and spatial organization shifts in human embryoid bodies.