BiophysicsbioRxivPreprint
Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids
D. Gagne, R. Azad, J. M. Aramini…·K. H. Gardner
This paper introduces a method using high-pressure NMR spectroscopy to identify proteins with internal ligand-binding voids by detecting nonlinear chemical shift changes in 1H/15N HSQC experiments.
DOI 10.1101/2020.08.25.267195