Author

E. A. Moreb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:E. coli· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. D. Lynch· 3 shared S. Li· 2 shared Z. Ye· 2 shared D. Baez Castellanos· 1 shared J. Lebeau· 1 shared J. N. Hennigan· 1 shared M. Hutmacher· 1 shared T. Yang· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

M. D. Lynch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dynamic control over feedback regulatory mechanisms improves NADPH fluxes and xylitol biosynthesis in engineered E. coli

S. Li, E. A. Moreb, Z. Ye, J. N. Hennigan, D. Baez Castellanos, T. Yang, M. D. Lynch

This study improves NADPH flux and xylitol production in engineered E. coli by dynamically controlling regulatory metabolites and metabolic pathways.

bioRxiv · Jul 27, 2020Bioengineering

Dynamic control over feedback regulation identifies pyruvate-ferredoxin oxidoreductase as a central metabolic enzyme in stationary phase E. coli.

S. Li, Z. Ye, J. Lebeau, E. A. Moreb, M. D. Lynch

This study uses dynamic metabolic control to enhance stationary phase biosynthesis in E. coli by targeting citrate synthase and glucose-6-phosphate dehydrogenase, leading to increased acetyl-CoA production and citramalic acid titers.

bioRxiv · Jul 26, 2020 · PreprintBiochemistry

CRISPR/Cas "non-target" sites inhibit on-target cutting rates

E. A. Moreb, M. Hutmacher, M. D. Lynch

This study shows that non-target PAM sites inhibit Cas9/gRNA on-target activity in a dose-dependent manner, suggesting strategies to improve Cas9 specificity.

bioRxiv · Jun 12, 2020Biochemistry