Author

E. A. Thim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. J. Price· 3 shared A. S. Mathew· 2 shared N. D. Sheybani· 2 shared A. L. Klibanov· 1 shared C. M. Gorick· 1 shared F. Rivera-Escalera· 1 shared G. W. Miller· 1 shared L. E. Petricca· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioengineering

R. J. Price

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation

E. A. Thim, L. E. Petricca, A. S. Mathew, F. Rivera-Escalera, M. R. Elliott, T. N. Bullock, R. J. Price

This paper shows that boiling histotripsy ablates melanoma and triggers abscopal tumor control by activating dendritic cells through antigen acquisition.

bioRxiv · Sep 2, 2023Bioengineering

Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound

E. A. Thim, T. Fox, T. Deering, L. R. Vass, N. D. Sheybani, M. Kester, R. J. Price

This study investigates whether combining focused ultrasound with C6-ceramide-loaded nanoliposomes enhances tumor control in 4T1 breast tumors, but finds limited synergy due to tumor resistance to C6.

bioRxiv · Mar 23, 2023Bioengineering

Transcriptomic Response of Brain Tissue to Focused Ultrasound-Mediated Blood-Brain Barrier Disruption Depends Strongly on Anesthesia

A. S. Mathew, C. M. Gorick, E. A. Thim, W. J. Garrison, A. L. Klibanov, G. W. Miller, N. D. Sheybani, R. J. Price

This study examines how different anesthetics affect the transcriptomic response of brain tissue to focused ultrasound-mediated blood-brain barrier disruption in mice.

bioRxiv · Jul 24, 2020Bioengineering