Pharmacology & ToxicologybioRxiv
Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants
DOI 10.1038/s41386-024-01914-2
Author
G. W. Miller
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2020-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 11 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- Pharmacology & ToxicologybioRxivPreprint
Paracetamol/acetaminophen hepatotoxicity: new markers for monitoring the elimination of the reactive N-Acetyl-p-benzoquinone imine
E. Gorrochategui, M. Le Vee, H. Selmi…·A. David
The paper identifies thiomethyl metabolites as new markers to monitor NAPQI elimination after therapeutic use or intoxication.
DOI 10.1101/2023.04.28.538718 - Pharmacology & ToxicologybioRxivPreprint
High-throughput Production of Diverse Xenobiotic Metabolites with P450-transduced Huh7 Hepatoma Cell Lines
C.-m. Lee, K. H. Liu, G. Singer…·E. T. Morgan
This paper develops P450-expressing Huh7 cell lines to generate xenobiotic metabolites, enabling high-throughput analysis of drug metabolism and identification of specific enzyme-substrate interactions.
DOI 10.1101/2022.03.12.484071 - Pharmacology & ToxicologybioRxivPreprint
Cross-species metabolomic analysis of DDT and Alzheimer's disease-associated tau toxicity
V. Kalia, M. M. Niedzwiecki, J. M. Bradner…·G. W. Miller
This study investigates the link between DDT exposure and tau toxicity in C. elegans and humans, finding that DDT exacerbates mitochondrial dysfunction caused by tau aggregation.
DOI 10.1101/2021.06.14.448355 - BioengineeringbioRxiv
ImmunoPET-informed sequence for focused ultrasound-targeted mCD47 blockade controls glioma
N. D. Sheybani, S. Paul, K. S. McCauley…·R. J. Price
This study shows that timing mCD47 antibody injection relative to focused ultrasound (FUS) BBB disruption affects antibody delivery to gliomas, with post-FUS injection improving delivery and reducing tumor growth.
DOI 10.1016/j.jconrel.2021.01.023 - BioengineeringbioRxiv
Transcriptomic Response of Brain Tissue to Focused Ultrasound-Mediated Blood-Brain Barrier Disruption Depends Strongly on Anesthesia
A. S. Mathew, C. M. Gorick, E. A. Thim…·R. J. Price
This study examines how different anesthetics affect the transcriptomic response of brain tissue to focused ultrasound-mediated blood-brain barrier disruption in mice.
DOI 10.1002/btm2.10198