Author

T. Fox

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Rizzi· 1 shared D. L. Mobley· 1 shared E. A. Thim· 1 shared H. Wang· 1 shared J. C. Cheung· 1 shared J. D. Chodera· 1 shared J. Jiang· 1 shared L. R. Vass· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiophysics

A. Rizzi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound

E. A. Thim, T. Fox, T. Deering, L. R. Vass, N. D. Sheybani, M. Kester, R. J. Price

This study investigates whether combining focused ultrasound with C6-ceramide-loaded nanoliposomes enhances tumor control in 4T1 breast tumors, but finds limited synergy due to tumor resistance to C6.

bioRxiv · Mar 23, 2023Bioengineering

Stretch and Twist of HEAT Repeats Leads to Activation of DNA-PK Kinase

X. Chen, X. Xu, Y. Chen, J. C. Cheung, H. Wang, J. Jiang, N. d. Val, T. Fox, M. Gellert, W. Yang

The paper reports cryoEM structures of DNA-PKcs in inactive and activated forms, revealing structural changes in HEAT repeats that drive kinase activation.

bioRxiv · Oct 19, 2020Biochemistry

Assessing the accuracy of octanol-water partition coefficient predictions in the SAMPL6 Part II log P Challenge

M. Isık, T. D. Bergazin, T. Fox, A. Rizzi, J. D. Chodera, D. L. Mobley

This paper evaluates the accuracy of octanol-water partition coefficient predictions in the SAMPL6 log P Challenge, finding improved performance compared to previous challenges and highlighting the effectiveness of various methods.

bioRxiv · Jan 20, 2020Biophysics