Author

E. A. Thomson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. Y. Poon· 2 shared H. Xu· 2 shared R. A. Lal· 2 shared S. Lee· 2 shared H. Moeller· 1 shared J. Annes· 1 shared J. P. Annes· 1 shared J. Sands· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

A. S. Y. Poon

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2 papers

Recent·Most cited

β-Cells as a Cell Factory for On-Demand Recombinant Protein Dosing: Harnessing the Neuroendocrine Cell Secretory Pathway for Controlled Release

A. S. Y. Poon, J. Annes, E. A. Thomson, R. A. Lal, H. Xu, S. Lee

This paper develops a β-cell-based platform for on-demand recombinant protein delivery by modifying the endogenous insulin processing pathway to produce and release therapeutic peptides like GLP-1 or glucagon.

bioRxiv · Jan 20, 2024 · PreprintBioengineering

Enhancing Therapeutic Insulin Transport from Macroencapsulated Islets Using Sub-Minute Pressure at Physiological Levels

A. S. Y. Poon, J. P. Annes, R. A. Lal, E. A. Thomson, H. Xu, S. Lee, H. Moeller, J. Sands

Applying sub-minute pressure at physiological levels enhances therapeutic insulin transport from macroencapsulated islets, enabling rapid glucose regulation in diabetic rodent models.

bioRxiv · Dec 11, 2023 · PreprintBioengineering