A Mechanistic Understanding of the Activity-Stability Trade-off in PETase
S. Chen, E. Akram, W. Qiao, Y. Zhang, S. Haider, Y. Cao
This study investigates the activity-stability trade-off in PETase using simulations and experiments, revealing how reshaping loop dynamics can enhance both stability and activity.
bioRxiv · Jun 9, 2024 · PreprintBiochemistry