Artificial Antigen Presenting Cells for Detection and Desensitisation of Auto-reactive T cells Associated with Type 1 Diabetes
A. Artzy-Schnirman, E. Abu-Shah, R. Chandrawati, E. Altman, N. Yusuf, S.-T. Wang, J. Ramos, C. Hansel, M. Haus-cohen, R. Dahan, S. Arif, M. L. Dustin, M. Peakman, Y. Reiter, M. M. Stevens
This paper develops artificial antigen presenting cells (aAPCs) to detect and desensitize autoreactive T cells in type 1 diabetes, showing effectiveness in human and mouse models.
bioRxiv · Dec 26, 2020 · PreprintBioengineering