A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging
L. Emmanouilidis, E. Bartalucci, Y. Kan, M. Ijavi, M. E. Perez, P. Afanasyev, D. Boehringer, J. Zehnder, S. H. Parekh, M. Bonn, T. C. T. Michaels, T. Wiegand, F. H.- T. Allain
This study investigates FUS liquid droplet maturation, revealing a solid beta-sheet surface layer that forms during aging, with RNA inhibiting this process.
bioRxiv · Jun 2, 2023Biochemistry