Author

Y. Kan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

H. Li· 2 shared H. Luo· 2 shared H.-Y. Zheng· 2 shared M.-X. Tang· 2 shared T. Dong· 2 shared T.-T. Pei· 2 shared Z.-H. Wang· 2 shared C. Niu· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

H. Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

LLPS condensates of Fha initiate the inside-out assembly of the type VI secretion system

T.-T. Pei, Y. An, X.-Y. Wang, H. Luo, Y. Kan, H. Li, M.-X. Tang, Z.-Y. Ye, J.-X. Liang, T. Jian, H.-Y. Zheng, Z.-H. Wang, X. Liang, M. Zhang, X. Liu, T. Dong

This study identifies Fha as the initiator of T6SS assembly in Acidovorax citrulli, showing it forms LLPS condensates that recruit T6SS components, revealing an inside-first assembly model.

bioRxiv · Dec 21, 2023 · PreprintMicrobiology

A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging

L. Emmanouilidis, E. Bartalucci, Y. Kan, M. Ijavi, M. E. Perez, P. Afanasyev, D. Boehringer, J. Zehnder, S. H. Parekh, M. Bonn, T. C. T. Michaels, T. Wiegand, F. H.- T. Allain

This study investigates FUS liquid droplet maturation, revealing a solid beta-sheet surface layer that forms during aging, with RNA inhibiting this process.

bioRxiv · Jun 2, 2023Biochemistry

Breaching the cell-envelope barriers of gram-positive and fungal microbes by a type VI secretion system in Acidovorax citrulli

T.-T. Pei, Y. Kan, Z.-H. Wang, M.-X. Tang, H. Li, S. Yan, Y. Cui, H.-Y. Zheng, H. Luo, T. Dong

This study identifies a type VI secretion system in Acidovorax citrulli that can breach gram-positive and fungal cell envelopes, with RhsB as a key effector.

bioRxiv · May 31, 2021 · PreprintMicrobiology

Temporal modulation of host aerobic glycolysis determines the outcome of M. marinum infection

L. Meng, L. Xie, Y. Kan, L. Liu, W. Dong, J. Feng, Y. Yan, G. Peng, M. Lu, C. Yang, C. Niu

This study shows that pre-infection modulation of host glycolysis with 2-DG enhances resistance to M. marinum infection by reducing phagocytosis and bacterial proliferation.

bioRxiv · Dec 27, 2018Microbiology