Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d
C. F. Almeida, D. Smith, T.-Y. Cheng, C. Harpur, E. Batleska, T. Nguyen, T. Hilmenyuk, C. V. Nguyen-Robertson, S. J. Reddiex, I. Van Rhijn, J. Rossjohn, A. P. Uldrich, B. Moody, S. J. Williams, D. G. Pellicci, D. I. Godfrey
This study identifies benzofuran sulfonates and small self-lipid antigens as activators of type II NKT cells via CD1d, revealing non-lipidic small molecules that trigger CD1d-restricted NKT cell responses.
bioRxiv · Mar 5, 2021Immunology