Distribution of droplets and immune responses after aerosol and intra-nasal delivery of influenza virus to the respiratory tract of pigs
V. Martini, M. Hinchcliffe, E. Blackshaw, M. Joyce, A. McNee, P. Beverley, A. Townsend, R. MacLoughlin, E. Tchilian
This study compares droplet distribution and immune responses from different delivery methods of influenza virus in pigs, finding MAD delivers high lung dose with systemic immune activation.
bioRxiv · Jun 4, 2020Immunology