Author

M. Joyce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:development & morphogenesis· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. L. Tyrrell· 3 shared J. Shields· 3 shared E. Arutyunova· 2 shared M. J. Lemieux· 2 shared A. Belovodskiy· 1 shared A. Landi· 1 shared A. McNee· 1 shared A. S. French· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersMicrobiology

D. L. Tyrrell

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Divergent evolution of sleep functions

M. Joyce, F. A. Falconio, L. Blackhurst, L. L. Prieto-Godino, A. S. French, G. F. Gilestro

This study shows that circadian-driven sleep is conserved across Drosophila species, but homeostatic regulation of sleep varies and evolved independently.

bioRxiv · May 27, 2023 · PreprintEvolutionary Biology

SARS-COV-2 Recombinant Receptor-Binding-Domain (RBD) Induces Neutralising Antibodies Against Variant Strains of SARS-CoV-2 and SARS-CoV-1

J. L. M. Law, M. Logan, M. Joyce, A. Landi, D. Hockman, K. Crawford, J. Johnson, G. LaChance, H. Saffran, J. Shields, E. Hobart, R. Brassard, E. Arutyunova, K. Pabbaraju, M. Croxen, , M. Houghton

This study shows that recombinant SARS-CoV-2 RBD induces neutralizing antibodies against variant strains and SARS-CoV-1, suggesting its potential as a vaccine candidate or booster.

bioRxiv · May 10, 2021Microbiology

Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2

S. Shahbaz, L. Xu, M. Osman, W. Sligl, J. Shields, M. Joyce, L. Tyrrell, O. Oyegbami, S. Elahi

The paper shows that CD45+CD71+ erythroid cells in COVID-19 patients express SARS-CoV-2 entry factors and are immunosuppressive, suggesting their involvement in hypoxia and erythropoiesis disruption.

bioRxiv · Aug 18, 2020Immunology

Distribution of droplets and immune responses after aerosol and intra-nasal delivery of influenza virus to the respiratory tract of pigs

V. Martini, M. Hinchcliffe, E. Blackshaw, M. Joyce, A. McNee, P. Beverley, A. Townsend, R. MacLoughlin, E. Tchilian

This study compares droplet distribution and immune responses from different delivery methods of influenza virus in pigs, finding MAD delivers high lung dose with systemic immune activation.

bioRxiv · Jun 4, 2020Immunology

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

W. Vuong, M. B. Khan, C. Fischer, E. Arutyunova, T. Lamer, J. Shields, H. A. Saffran, R. T. McKay, M. J. van Belkum, M. Joyce, H. S. Young, D. L. Tyrrell, J. C. Vederas, M. J. Lemieux

This paper shows that feline coronavirus drugs inhibit SARS-CoV-2 main protease and block virus replication in cell culture with low toxicity.

bioRxiv · May 3, 2020Biochemistry

Induction of differentiation and metabolic reprogramming in human hepatoma cells by adult human serum

R. H. Steenbergen, M. Oti, R. ter Horst, W. Tat, C. Neufeldt, A. Belovodskiy, T. T. Chua, W. J. Cho, M. Joyce, B. E. Dutilh, D. L. Tyrrell

This study shows that culturing human hepatoma cells in adult human serum restores liver-like morphology, metabolism, and organ-specific functions, suggesting that FBS may suppress these features.

bioRxiv · Aug 25, 2017Cell Biology