Author

E. Braud

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Caflisch· 1 shared D. Coelho· 1 shared D. Huang· 1 shared I. Corbeski· 1 shared J. Deng· 1 shared L. Iannazzo· 1 shared M. Etheve-Quelquejeu· 1 shared P. A. Vargas-Rosales· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Caflisch

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1 paper

Recent·Most cited

The catalytic mechanism of the RNA methyltransferase METTL3

I. Corbeski, P. A. Vargas-Rosales, R. K. Bedi, J. Deng, D. Coelho, E. Braud, L. Iannazzo, Y. Li, D. Huang, M. Etheve-Quelquejeu, Q. Cui, A. Caflisch

This study reveals the catalytic mechanism of METTL3-14 by identifying two adenosine binding conformations, the methyl transfer transition state, and the roles of key residues in catalysis.

bioRxiv · Sep 6, 2023 · PreprintBiochemistry