Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of Nsp1, Nsp2, and Nucleocapsid proteins from SARS-CoV-2
M. Slavin, J. Zamel, K. Zohar, S. Eliyahu, M. Braitbard, E. Brielle, L. Baraz, M. Stolovich-Rain, A. Friedman, D. G. Wolf, A. Rouvinski, M. Linial, D. Schneidman-Duhovny, N. Kalisman
This study uses targeted in situ CLMS and integrative modeling to determine the structures of SARS-CoV-2 Nsp1, Nsp2, and N proteins, revealing key interactions and functional insights.
bioRxiv · Feb 4, 2021Biochemistry