M. Linial

The Interactome of DUX4 Reveals Multiple Activation Pathways

This study identifies new DUX4 protein interactions and activation pathways using AP-MS and CL-MS, revealing structural and functional insights into its role in FSHD.

Alteration in long noncoding RNAs in response to oxidative stress and ladostigil in SH-SY5Y cells

This study investigates how oxidative stress and ladostigil affect lncRNA expression in SH-SY5Y cells, identifying key lncRNAs involved in redox homeostasis and neurodegeneration.

Ladostigil attenuates the oxidative and ER stress in human neuroblast-like SH-SY5Y cells

This study shows that ladostigil reduces oxidative and ER stress in SH-SY5Y cells, potentially mitigating neurotoxicity and cell death in aging brains.

Chromoanagenesis landscape in 10,000 TCGA patients

This study analyzes chromoanagenesis in 10,000 TCGA cancer patients using a machine learning algorithm, revealing cancer-type specific patterns and gene interactions.

Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of Nsp1, Nsp2, and Nucleocapsid proteins from SARS-CoV-2

This study uses targeted in situ CLMS and integrative modeling to determine the structures of SARS-CoV-2 Nsp1, Nsp2, and N proteins, revealing key interactions and functional insights.

The FABRIC Cancer Portal: A Ranked Catalogue of Gene Selection in Tumors over the Human Coding Genome

The FABRIC Cancer Portal ranks gene selection in tumors across 33 cancer types and the human coding genome using genomic and proteomic data.

Spliceosome-Associated MicroRNAs Identified in Breast Cancer Cells Act on Nuclear Targets and Are Potential Indicators for Tumorigenicity

The paper identifies spliceosome-associated miRNAs in breast cancer cells that act as tumor suppressors in the nucleus and may be targets for therapeutic intervention.

Substantial Batch Effects in TCGA Exome Sequences Undermine Pan-Cancer Analysis of Germline Variants

This study identifies substantial batch effects in TCGA exome sequences that affect germline variant analysis across cancer types.