N. Kalisman

This study identifies new DUX4 protein interactions and activation pathways using AP-MS and CL-MS, revealing structural and functional insights into its role in FSHD.

The paper identifies a compact, stable dimeric conformation of α-synuclein that may promote dityrosine linkage and is implicated in Parkinson's disease.

The paper identifies a compact apo-σ70 conformation in vitro and in vivo using CL-MS, suggesting it may be transcriptionally inactive and activated upon RNAP binding.

This study uses targeted in situ CLMS and integrative modeling to determine the structures of SARS-CoV-2 Nsp1, Nsp2, and N proteins, revealing key interactions and functional insights.

This study maps the conformational space of α-synuclein monomer using simulations and experimental validations, revealing stable conformations with slow interconversion times.

This study uses mass spectrometry to show that formaldehyde cross-linking in proteins involves two carbon atoms, not one, and identifies new structural insights from cross-links in human cells.