Author

E. Brosens

Primary ORCID profile (0000-0001-8235-4010 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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E. BrosensiD1 paper · Erasmus MC

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Assay:protein structure· 1

Frequent Co-Authors

A. A. Sablina· 1 shared A. De Klein· 1 shared A. J. Eggink· 1 shared A. N. Volkov· 1 shared A. Sheryazdanova· 1 shared A. Wohlkonig· 1 shared B. Fischer· 1 shared C. M. Ten Broek· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. A. Sablina

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2 papers

Recent·Most cited

Competitive, connective and allosteric Nanobodies that modulate the SOS1-RAS protein-protein interactions and tune the nucleotide exchange rate as a starting point for drug design

B. Fischer, T. Uchanski, A. Sheryazdanova, S. Gonzalez, A. N. Volkov, E. Brosens, T. Zogg, V. V. Kalichuk, S. Ballet, W. Versees, A. A. Sablina, E. Pardon, A. Wohlkonig, J. Steyaert

The paper introduces methods to discover Nanobodies that modulate SOS1-RAS interactions and nucleotide exchange rates, with potential applications in drug design.

bioRxiv · Dec 6, 2022 · PreprintBioengineering

Abnormal vertebral patterns in genetically heterogeneous deceased fetuses and neonates: evidence of selection against variations

P. C. Schut, E. Brosens, F. Galis, C. M. Ten Broek, I. M. Baijens, M. H. Dremmen, D. Tibboel, M. P. Schol, A. De Klein, A. J. Eggink, T. E. Cohen-Overbeek

The paper examines vertebral abnormalities in deceased fetuses and neonates, finding a high prevalence of cervical ribs and suggesting genetic heterogeneity in their development.

bioRxiv · Oct 1, 2019 · PreprintEvolutionary Biology