Author

E. Cassol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Kumar· 2 shared A. Abizaid· 1 shared A. Edwards· 1 shared A. Golshani· 1 shared A. Jaworski· 1 shared D. Ahmed· 1 shared D. Roy· 1 shared H. Ali· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

A. Kumar

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2 papers

Recent·Most cited

Differential remodeling of the electron transport chain is required to support TLR3 and TLR4 signaling and cytokine production in macrophages

D. Ahmed, D. Roy, A. Jaworski, A. Edwards, A. Abizaid, A. Kumar, A. Golshani, E. Cassol

The paper shows that TLR3 and TLR4 signaling in macrophages involves differential remodeling of the electron transport chain, which affects ROS production and cytokine responses.

bioRxiv · Aug 21, 2019Immunology

Inhibitor of apoptosis, IAP, genes play a critical role in the survival of HIV-infected macrophages

A. Kumar, R. E. H. Caballero, S. X. M. Dong, N. Gajanayaka, H. Ali, E. Cassol, W. Cameron, R. Korneluk, M. Tremblay, J. Angel

This study shows that SMAC-mimetics induce apoptosis in HIV-infected macrophages by targeting IAPs, suggesting IAP modulation as a strategy for eliminating viral reservoirs.

bioRxiv · Feb 6, 2019 · PreprintImmunology