Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts
E. D. Jensen, M. Deichmann, X. Ma, R. U. Vilandt, G. Schiesaro, M. B. Rojek, B. Lengger, L. Eliasson, J. M. Vento, D. Durmusoglu, S. P. Hovmand, I. Al'Abri, J. Zhang, N. C. Crook, M. K. Jensen
The paper demonstrates mating between haploid cells with human GPCRs and enables hGPCR signaling in probiotic yeast using transcriptome analysis and ligand-free screening.
bioRxiv · Jan 11, 2022Cell Biology