Cell BiologybioRxiv
Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses
K. Kolmus, P. Erdenebat, B. Stewig…·M. Miaczynska
The paper shows that depletion of Vps37 proteins destabilizes ESCRT-I, leading to cell growth inhibition and sterile inflammation in colorectal cancer.
DOI 10.1242/jcs.250951