Author

E. Doerffler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Nayak· 1 shared A. Tomkinson· 1 shared A. Vijjapurapu· 1 shared B. Goyal· 1 shared B. Ma· 1 shared B. Marchand· 1 shared C. Palmiotti· 1 shared D. Rautiola· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Nayak

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1 paper

Recent·Most cited

Discovery and Synthesis of GS-7682, a Novel Prodrug of a 4'-CN-4-Aza-7,9-Dideazaadenosine C-Nucleoside with Broad-Spectrum Potency Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

D. S. Siegel, H. C. Hui, J. Pitts, M. S. Vermillion, K. Ishida, D. Rautiola, M. Keeney, H. Irshad, L. Zhang, K. Chun, G. Chin, B. Goyal, E. Doerffler, H. Yang, M. O. Clarke, , R. L. Mackman

This paper describes the discovery and synthesis of GS-7682, a prodrug with broad antiviral activity against RSV and other viruses, showing efficacy in RSV-infected monkeys.

bioRxiv · Apr 17, 2024 · PreprintBiochemistry