Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips
Z. Izadifar, J. Cotton, C. Chen, N. A. Bustos, V. Horvath, A. Stejskalova, C. Wu, A. Gulati, N. T. LoGrande, B. Budnik, S. Shahriar, E. Doherty, T. To, S. E. Gilpin, A. M. Sesay, , D. E. Ingber
This paper develops human cervical Organ Chip models to study mucus production, host-microbiome interactions, and immune responses, showing they mimic in vivo conditions and respond to microbiome changes.
bioRxiv · Feb 22, 2023 · PreprintBioengineering