Chromatin accessibility combined with enhancer clusters activation mediates heterogeneous response to dexamethasone in myeloma cells
V. GABORIT, J. CRUARD, C. Guerin-Charbonnel, J. Derrien, J.-B. Alberge, E. Douillard, N. Roi, M. Devic, L. Campion, F. Westermann, P. Moreau, C. Herrmann, J. Bourdon, F. Magrangeas, S. Minvielle
The paper investigates how chromatin accessibility and enhancer clusters mediate heterogeneous responses to dexamethasone in myeloma cells, showing epigenomic changes linked to transcriptional heterogeneity.
bioRxiv · Sep 6, 2021 · PreprintCancer Biology