The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability
J. Derrien, C. Guerin-Charbonnel, V. Gaborit, L. Campion, M. Devic, E. Douillard, N. Roi, H. Avet-Loiseau, O. Decaux, T. Facon, J.-P. Mallm, R. Eils, N. C. Munshi, P. Moreau, C. Herrmann, , S. Minvielle
This study examines DNA methylation heterogeneity in multiple myeloma, linking it to transcriptomic variability and poor patient outcomes through epigenetic and structural changes.
bioRxiv · Oct 1, 2020 · PreprintCancer Biology