Adipocyte-specific modulation of KLF14 expression in mice leads to sex-dependent impacts in adiposity and lipid metabolism
Q. Yang, J. Hinkle, J. N. Reed, R. Aherrahrou, Z. Xu, T. E. Harris, E. E. Stephenson, K. Musunuru, S. R. Keller, M. Civelek
This study shows that adipocyte-specific KLF14 modulation in mice has sex-dependent effects on adiposity and lipid metabolism, with female mice showing increased fat mass and altered lipid storage when KLF14 is deficient.
bioRxiv · Sep 15, 2021Physiology