Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin
E. S. Niedzialkowska, L. Runyan, E. Kudryashova, E. Egelman, D. S. KUDRYASHOV
This study shows that Salmonella effector SipA stabilizes F-actin through a unique binding mechanism, similar to inorganic phosphate and phalloidin, enhancing toxin effects while avoiding host detection.
bioRxiv · Dec 26, 2023 · PreprintBiochemistry